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Acetone Cyanohydrin or 2-Hydroxyisobutyronitrile or 2-Hydroxy-2-methylpropanenitrile SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative |
Email: info@ammol.org |
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Acetone Cyanohydrin or 2-Hydroxyisobutyronitrile or 2-Hydroxy-2-methylpropanenitrile
CAS Number: 75-86-5
Molecular Formula: C4H7NO
Molecular Weight: 85.10
Acetone Cyanohydrin or 2-Hydroxyisobutyronitrile or 2-Hydroxy-2-methylpropanenitrile
Acetone Cyanohydrin or 2-Hydroxy-2-methylpropanenitrile or 2-Hydroxyisobutyronitrile SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 03-Feb-26
Section 1. Product Information
Product Name & Other Names: Acetone Cyanohydrin or 2-Hydroxy-2-methylpropanenitrile or 2-Hydroxyisobutyronitrile.
CAS No.: 75-86-5
EINECS EC Number: 200-909-4
Chemical Formula: C4H7NO
Molecular Weight: 85.10
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 2), H300
Acute toxicity, Dermal (Category 1), H310
Acute toxicity, Inhalation (Category 2), H330
Long-term (chronic) aquatic hazard (Category 1), H410
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Aquatic Toxicity | GHS Label Elements  Toxic |
Signal Words: Danger
Hazard statements:
H300 Fatal if swallowed.
H310 Fatal in contact with skin.
H330 Fatal if inhaled.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P314: Get medical advice/attention if you feel unwell.
P330: Rinse mouth.
P301+310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+361+353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P333+313: If skin irritation or a rash occurs: Get medical advice/attention.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P303+361+353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P391: Collect spillage.
P405: Store locked up.
P403+233: Store in a well-ventilated place. Keep container tightly closed.
P501: Dispose of contents/container in accordance with local/regional/national/international regulation.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Acetone Cyanohydrin or 2-Hydroxy-2-methylpropanenitrile or 2-Hydroxyisobutyronitrile.
CAS No.: 75-86-5
EINECS EC Number: 200-909-4
Section 4. First Aid & Procedure
Always get medical attention after the first aid is over.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin: Immediately flush skin with plenty of water for at least 15 minutes. Remove and wash contaminated clothing and shoes before reuse. Get medical attention if irritation develops.
Eyes: Immediately flush eyes with plenty of water for 15 minutes, occasionally lifting upper and lower eyelids. Hold eyelids apart during irrigation. Get medical attention.
Inhalation: Remove person to fresh air. If breathing is difficult, give oxygen. If not breathing administer artificial respiration. Get medical attention.
Section 5. Fire Fighting Measures
Fire/Explosion: Flash Point: 75C. Combustible.
Extinguishing Medium: Water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance/ mixture: Carbon oxides, Hydrogen cyanide gas, fumes.
Fire Fighting Instructions: Use suitable protective equipment for surrounding fire.
Special Information In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6. Spills and Disposals
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
Section 7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation.In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, Acids, Bases.
Section 8. Exposure Controls & Personal Protection
Exposure Limits:
USA.ACCGIH: Ceiling: 5 mg/m3 Skin.
Engineering Controls: Use adequate exhaust ventilation to keep airborne concentrations below the allowable exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9. Physical & Chemical Data
Appearance: Clear Colorless to Pale Yellow Liquid.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: 0.932
Melting point/freezing point: -21.2C.
Initial boiling point and boiling range: 95C.
Flash point: 75C.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Chemical Formula: C4H7NO
Molecular Weight: 85.10
Section 10. Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Incompatibility (Materials to Avoid): Strong oxidizing agents, Acids, Bases.
Conditions to Avoid: Incompatible materials, exposure to excessive heat.
Hazardous Decomposition Products: Carbon oxides, Hydrogen cyanide gas, fumes.
Hazardous Polymerization: Will not occur.
Section 11. Toxicological Information
Toxicity to Animals:
LD50 Oral Rat: 16 mg/kg.
LD50 Dermal Rabbit: 5.1 mg/kg
Acute toxicity estimate Inhalation - 4 h - 0,6 mg/l - vapor.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12. Ecological Information
Toxicity to fish: static test LC50 - Oncorhynchus mykiss (rainbow trout) - 0,22 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - 0,13 mg/l - 48 h.
Ecotoxicity: Very toxic to aquatic organisms, may cause long-term adverse effects.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
Section 13. Disposal Suggestions
Dispose of in accordance with all applicable local, state, and federal regulations at an approved waste disposal facility.
Section 14. Transport and Label Information
DOT (USA) & ADR/RID Europe:
UN-No UN 1541
Proper Shipping Name: Acetone cyanohydrin, stabilized
Hazard Class 6.1; Packing Group I
IMDG/IMO
UN-No UN 1541
Proper Shipping Name: Acetone cyanohydrin, stabilized
Hazard Class 6.1; Packing Group I
IATA:
UN-No UN 1541
Proper Shipping Name: Acetone cyanohydrin, stabilized
Hazard Class 6.1; Packing Group I.
Section 15. Regulatory Information
USA:
SARA 311/312 Hazards: Acute Health Hazard, Chronic Health Hazard. See section 2.
Section 16. Other Information
European Labeling in Accordance with EC Directives:
H300 Fatal if swallowed.
H310 Fatal in contact with skin.
H330 Fatal if inhaled.
H410 Very toxic to aquatic life with long lasting effects.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org