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Bedaquiline
CAS Number: 843663-66-1
Molecular Formula: C32H31BrN2O2
Molecular Weight: 555.52
Bedaquiline
Bedaquiline SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 25-August-2026
Section 1: Product and Company Identification
Product Name & Other Names: Bedaquiline.
CAS No.: 843663-66-1
EINECS, EC Number: 831-215-5
Molecular Weight: 555.52
Chemical Formula: C32H31BrN2O2
Relevant uses and uses advised against (if any): Laboratory chemicals, Manufacture of substances
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Specific target organ toxicity - repeated exposure (Category 2), H373
Chronic aquatic toxicity (Category 1), H410
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements Harmful | GHS Label Elements Organ Damage | GHS Label Elements Aquatic Toxicity |
Signal Words: Danger
Hazard statements:
H302: Harmful if swallowed.
H373: May cause damage to organs through prolonged or repeated exposure.
H410: Very toxic to aquatic life with long lasting effects.
Precautionary statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P314: Get Medical advice/attention if you feel unwell.
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Section 3: Composition / Information on Ingredients
Product Name & Other Names: Bedaquiline.
CAS No.: 843663-66-1
EINECS, EC Number: 831-215-5
Section 4: First Aid Measures
Always seek medical attention after first aid measures are provided.
Eyes: Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally.
Skin: Immediately flush skin with excess water for 15 minutes while removing contaminated clothing.
Ingestion: Call Emergency Medical immediately. Rinse mouth with cold water. Give victim 1-2 cups of water or milk to drink. Induce vomiting immediately.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration.
Section 5: Fire Fighting Measures
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Protective equipment and precautions for firefighters: Use water spray, foam, or dry chemical to extinguish fire. Firefighters should wear full firefighting turn-out gear and respiratory protection. Cool container with water spray.
Special hazards arising from the substance: Carbon oxides, Nitrogen oxides (NOx), Bromine compounds.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapor, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allowing it to evacuate as per law.
Section 7: Handling and Storage Green
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: Refrigeration is ok. Freezer is good. Short term shipping may be at room temperature.
Section 8: Exposure Controls / Personal Protection
Exposure guidelines: Not Available.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
Section 9: Physical and Chemical Properties
Physical state and appearance: White to almost white powder.
Odor: No data found.
Odor threshold: No data found.
pH (1% soln/water): No data found.
Relative density: No data found.
Melting Point: 118C literature.
Initial boiling point and boiling range: No data found.
Flash point: No data found.
Auto-ignition temperature: No data found.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility: Insoluble in water. It is soluble in organic solvents, such as DMSO methanol and dimethyl formamide.
Viscosity: No data found.
Section 10: Stability and Reactivity
Stability: Stable under normal conditions of use and storage.
Incompatibility: Heat and strong oxidizing agents.
Hazardous Decomposition Products: Carbon oxides, Nitrogen oxides (NOx), Bromine compounds.
Hazardous Polymerization: Has not been reported.
Section 11: Toxicology Information
Toxicity Data: No data found.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by IARC.
May cause damage to organs through prolonged or repeated exposure.
Reproductive Effects: No data found.
Developmental Effects: No data found.
Teratogenicity: No data found.
Section 12: Ecological Information
Toxicity to fish: No data found.
Ecotoxicity (aquatic and terrestrial): Toxic to terrestrial and aquatic plants and animals. Do not release to environment.
Results of PBT and vPvB assessment: No data found.
Section 13: Disposal Considerations
Check with all applicable local, regional, and national laws and regulations.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe:
UN-No: UN3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. ((αS,βR)-6-Bromo-α-[2 (dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3 quinolineethanol).
Hazard Class: 9; Packing Group: III
IATA & IMDG/IMO
UN-No: UN3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. ((αS,βR)-6-Bromo-α-[2 (dimethylamino)ethyl]-2-methoxy-α-1-naphthalenyl-β-phenyl-3 quinolineethanol).
Hazard Class: 9; Packing Group: III.
Section 15: Regulatory Information
USA:
SARA 311/312 Hazard Categories: See section 2/
California Proposition 65: Not listed for cancer, birth defects or reproductive harm.
Section 16: Other Information
European Labeling in Accordance with EC Directives:
H302: Harmful if swallowed.
H373: May cause damage to organs through prolonged or repeated exposure.
H410: Very toxic to aquatic life with long lasting effects.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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Please visit Main Page of Bedaquiline Suppliers.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org