American Molecules - Ammol.org USA

1-(2-Hydroxyethyl)piperazine or 1-(2-Hydroxyethyl) Piperazine or Piperazine-1-ethanol or 2-Piperazinoethanol SDS of Supplier Exporter Manufacturers' Representative

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1-(2-Hydroxyethyl)piperazine or 1-(2-Hydroxyethyl) Piperazine or Piperazine-1-ethanol or 2-Piperazinoethanol
CAS Number: 103-76-4

Molecular Formula: C6H14N2O
Molecular Weight: 130.19

1-(2-Hydroxyethyl)piperazine or 2-Piperazinoethanol Suppliers
1-(2-Hydroxyethyl)piperazine or 1-(2-Hydroxyethyl) Piperazine or Piperazine-1-ethanol or 2-Piperazinoethanol

1-(2-Hydroxyethyl)piperazine or 1-(2-Hydroxyethyl) Piperazine or 2-Piperazinoethanol or Piperazine-1-ethanol SDS GHS, Safety Data Sheet
MSDS GHS, Material Safety Data Sheet
 01-Feb-26

1. Product Identification

Product Name & Other Names: 1-(2-Hydroxyethyl)piperazine or 1-(2-Hydroxyethyl) Piperazine or 2-Piperazinoethanol or Piperazine-1-ethanol.
CAS No.: 103-76-4
EINECS EC No.: 203-142-3
Molecular Formula: C6H14N2O
Molecular Weight: 130.19
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
:

Skin irritation (Category 2), H315
Serious eye damage (Category 1), H318

Labeling according to Regulation (EC) No 1272/2008

GHS Label Elements
Corrosive
Corrosive

Signal Words: Danger

Hazard statements:
H315 Causes skin irritation.
H318 Causes serious eye damage.

Precautionary statements:
P210: Keep away from heat/sparks/open flames/hot surfaces – No smoking.
P233: Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P303+361+353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.

3. Composition/Information on Ingredients

Product Name & Other Names: 1-(2-Hydroxyethyl)piperazine or 1-(2-Hydroxyethyl) Piperazine or 2-Piperazinoethanol or Piperazine-1-ethanol.
CAS No.: 103-76-4
EINECS EC No.: 203-142-3

4. First Aid Measures

Always seek medical attention after first aid measures are provided.

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

5. Fire Fighting Measures

Fire: May catch fire at high temperature.
Products of Combustion: Carbon oxides, Nitrogen oxides (NOx) and fumes.
Fire Extinguishing Media: Use water spray or fog, alcohol-resistant foam, dry chemical, sand, or carbon dioxide. Cool containing vessels with water jet to prevent pressure build-up, auto-ignition, or explosion. Do not allow run-off from firefighting to enter drains or water courses.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.

6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
Small Spill: Avoid mist formation. Avoid breathing mist. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Remove all sources of ignition. Provide proper ventilation. Absorb the material on a porous, inert material such as earth, sand, or vermiculite. If solid/powder - carefully sweep up the material without causing dust. Dispose of in accordance with local regulations.

7. Handling and Storage

Precautions for safe handling: Keep away from sources of ignition - No smoking. Take measures to prevent the build-up of electrostatic charge. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, Acid anhydrides, Acids. Keep the product in its original container well sealed, in a dry and ventilated area, away from potential sources of ignition and protected from light. Protect against physical damage. Storage: Room temperature.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. Physical and Chemical Properties

Appearance: Colorless to slight yellowish liquid. Air Sensitive.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative Density: about 1.06
Boiling Point: 246C literature.
Melting Point: -39C literature.
Flash Point: 124C literature.
Auto-ignition Temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Pressure (mm Hg): Not available.
Vapor Density (Air=1): Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Miscible with water.
Viscosity: Not available.
Molecular Formula: C6H14N2O
Molecular Weight: 130.19

10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage. Vapor/air-mixtures are explosive at intense warming.
Hazardous Decomposition Products: It emits Carbon oxides, Nitrogen oxides (NOx) and fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents, Acids.
Conditions to Avoid: Incompatibles, Air, Moisture, Heat, flames, and sparks & light.

11. Toxicological Information

Toxicity data
LD50 Oral - Rat - 4244 mg/kg.
LD50 Dermal - Rabbit - >5000 mg/kg.
Carcinogenicity: Not established as a carcinogen by any agency.
Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found.

12. Ecological Information

Toxicity to fish: flow-through test LC50 - Pimephales promelas (fathead minnow) - 6.410 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: semi-static test NOEC - Daphnia magna (Water flea) - >= 12 mg/l - 21 d
Persistence and Degradability: No information available. Persistence is unlikely.
Mobility: Will be mobile in the environment.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.

14. Transport Information

USA DOT Classification: Not regulated.
Canada TDG Classification: Not regulated.
IATA & ADR/RID Europe: Not regulated.

15. Regulatory Information

USA:
SARA 311/312 Hazards
: Immediate Health Hazard: Acute Yes, Chronic Health Hazard.
California Proposition 65: This product does not contain any Proposition 65 chemicals.

16. Other Information

European Labeling in Accordance with EC Directives:
H315 Causes skin irritation.
H318 Causes serious eye damage.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.

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Suppliers and Manufacturers' Representative:
American Molecules - Ammol.org USA
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org

1 February, 2026