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Nicotinamide or Niacinamide or Vitamin B3 SDS Safety Data Sheet of Supplier Exporter Manufacturers' Representative |
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Nicotinamide or Niacinamide or Vitamin B3
CAS Number: 98-92-0
Molecular Formula: C6H6N2O
Molecular Weight: 122.13
Nicotinamide or Niacinamide or Vitamin B3
Nicotinamide or Niacinamide or Nicotinic Amide or Pyridinecarboxamide or Vitamin B3 SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 25-Jan-25
1. Product Identification
Product Name & Other Names: Nicotinamide or Niacinamide or Nicotinic Amide or Pyridinecarboxamide or Vitamin B3.
CAS No.: 98-92-0
EINECS: EC Number: 202-713-4
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: As per letterhead above.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Serious eye damage/eye irritation Category 2A
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Irritant |
Signal Words: Warning
Hazard statements:
H319: Causes serious eye irritation.
Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352-IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/ attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Nicotinamide or Niacinamide or Nicotinic Amide or Pyridinecarboxamide or Vitamin B3.
CAS No.: 98-92-0
EINECS: EC Number: 202-713-4
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: Combustible at high temperature.
Auto-Ignition Temperature: 480C literature.
Products of Combustion: Nitrogen oxides, Carbon dioxide, Carbon monoxide, fumes.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.Avoid solid water jet as it can scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill: Contain spilled material. Avoid touching the spilled material. Do not let the product enter drains. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Do not ingest. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: Room Temperature.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not Established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.
9. Physical and Chemical Properties
Appearance: White crystalline powder.
Odor: Practically odorless.
Odor threshold: Not applicable.
pH: 6.0-7.5 @ 20C 5% for aq. solution.
Relative density: about 1.40 @ 25C.
Boiling Point: Not available.
Melting Point: 128C - 131C.
Flash point: No information found.
Auto-ignition temperature: 480C literature.
Decomposition temperature: No information found.
Upper/lower flammability or explosive limits: No information found.
Vapor pressure: No information found.
Vapor density: No information found.
Evaporation rate: No information found.
Flammability (solid, gas): No information found.
Partition coefficient: n-octanol/water: No information found.
Solubility: Soluble in water.
Viscosity: No information found.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits Oxides of Nitrogen, Carbon dioxide, Carbon monoxide & Fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles, heat & light, spark, flame.
11. Toxicological Information
Toxicity data
LD50 Oral - Rat - > 2500 mg/kg
LD50 Dermal - Rabbit - > 2,000 mg/kg
Carcinogenic Effects: Not know as carcinogen.
Mutagenic Effects: No information found.
Reproductive Effects: No information found.
12. Ecological Information
Toxicity to fish: static test LC50 - Poecilia reticulata (guppy) - > 1.000 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - > 1.000 mg/l - 24 h.
Persistence and Degradability: Soluble in water Persistence is unlikely based on information available.
Mobility: Will likely be mobile in the environment due to its water solubility.
Bioaccumulation/ Accumulation: Degradable.
Results of PBT and vPvB assessment: No information found for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Follow all the pollution control rules..
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IATA & IMDG/IMO: Not dangerous goods.
15. Regulatory Information
USA:
SARA 311/312 Hazards: See section 2.
California prop. 65: Not listed.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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