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Toll Free: 1-855-55-AMMOLMethanesulfonic Acid or Mesylate or Methanesulphonic Acid
CAS Number: 75-75-2
Molecular Formula: CH3SO3H
Molecular Weight: 96.11
Methanesulfonic Acid or Mesylate or Methanesulphonic AcidMethanesulfonic Acid or MSA or Methanesulphonic acid or Mesylate
SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 20-August-2026Section 1: Product and Company Identification
Product Name & Other Names: Methanesulfonic Acid or MSA or Methanesulphonic acid or Mesylate.
CAS No.: 75-75-2
EINECS, EC Number: 200-898-6
Molecular Weight: 96.11
Chemical Formula: CH43S or CH3SO3H
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: American Molecules, 9910 Bent Oak Dr, Houston, TX 77040, USA.
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665.
In case of emergency contact: Will be given with the supply.Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008Corrosive to metals Category 1, (H290)
Acute toxicity, Oral Category 4, (H302)
Acute toxicity, Dermal Category 4, (H312)
Skin corrosion Category 1B, (H314)
Specific target organ toxicity - single exposure Category 3, Respiratory system, (H335)Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements
CorrosiveSignal Words: Warning
Hazard statements:
H290: May be corrosive to metals.
H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H314: Causes severe skin burns and eye damage.
H335: May cause respiratory irritation.Precautionary statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P330: Rinse mouth
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P501: Dispose of contents/container in accordance with local/regional/national/international regulation.Section 3: Composition / Information on Ingredients
Product Name & Other Names: Methanesulfonic Acid or MSA or Methanesulphonic acid or Mesylate.
CAS No.: 75-75-2
EINECS, EC Number: 200-898-6Section 4: First Aid Measures
Always seek medical attention after first aid measures are provided.
Eyes: Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally.
Skin: Immediately flush skin with excess water for 15 minutes while removing contaminated clothing.
Ingestion: Call Emergency Medical immediately. Rinse mouth with cold water. Give victim 1-2 cups of water or milk to drink. Induce vomiting immediately.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration.Section 5: Fire Fighting Measures
It is not a flammable solid. However, it will burn at high temperature. When heated to decomposition, it emits acrid fumes.
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Unsuitable extinguishing media: Water, Foam. The product reacts with water and generates heat.
Special hazards arising from the substance or mixture: Carbon oxides, sulfur oxides.
Protective equipment and precautions for firefighters: Use foam or dry chemical to extinguish fire. Firefighters should wear full fire fighting turn-out gear and respiratory protection. Cool container with water spray.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.Section 7: Handling and Storage Green
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.).
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, alkalis, strong reducing agents, amines, hydrogen fluoride, acids, strong alkalis, bases, water.Section 8: Exposure Controls / Personal Protection
Use ventilation to keep airborne concentrations below exposure limits. Have approved eyewash facility, safety shower, and fire extinguishers readily available. Wear chemical splash goggles and chemical resistant clothing such as gloves and aprons. Wash hands thoroughly after handling material and before eating or drinking. Use NIOSH-approved respirator with a dust cartridge.
Exposure guidelines: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice.Section 9: Physical and Chemical Properties
Physical state and appearance: Clear liquid.
Odor: around 1.48.
Odor threshold: No data found.
pH: No data found.
Relative density: around 1.48.
Melting Point: 20C.
Initial boiling point and boiling range: 167C @ 10mm Hg.
Flash point: 189C.
Auto-ignition temperature: >500C.
Decomposition temperature: No data found.
Upper/lower flammability or explosive limits: No data found.
Vapor pressure: No data found.
Vapor density: No data found.
Evaporation rate: No data found.
Flammability (solid, gas): No data found.
Partition coefficient: n-octanol/water: No data found.
Solubility(ies): Miscible with water. Miscible with methanol, diethyl ether. Immiscible with hexane.
Viscosity: No data found.Section 10: Stability and Reactivity
Avoid heat and ignition sources.
Stability: Stable under normal conditions of use and storage.
Incompatibility: Strong oxidizing strong alkalis, strong reducing agents, amines, hydrogen fluoride, acids, strong alkalis, bases, water. Avoid various metals like iron, copper, brass, mild steel.
Hazardous decomposition products formed under fire conditions: Carbon oxides, sulfur oxides.Section 11: Toxicology Information
LD50 oral, rat: 649 mg/kg.
LD50 dermal rabbit: > 1,000 mg/kg.
Carcinogenicity: Not defined as a carcinogen to humans by IARC, NTP, OSHA and ACGIH.
Mutagenic Effects: No data found.
Teratogenic Effects: No data found.
Developmental Toxicity: No data found.
Reproductive Effects: No data found.Section 12: Ecological Information
Toxicity to fish: static test LC50 - Oncorhynchus mykiss (rainbow trout) - 73 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - 70 mg/l - 48 h.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.Section 13: Disposal Considerations
Check with all applicable local, regional, and national laws and regulations.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe:
UN number: 3265
UN proper shipping name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. (Methanesulphonic acid)
Class: 8, Packing Group: II.
IMDG/IMO & IATA:
UN number: 3265
UN proper shipping name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. (Methanesulphonic acid)
Class: 8, Packing Group: II.Section 15: Regulatory Information
No further data available.
Section 16: Other Information
European Labeling in Accordance with EC Directives:
H290: May be corrosive to metals.
H302: Harmful if swallowed.
H312: Harmful in contact with skin.
H314: Causes severe skin burns and eye damage.
H335: May cause respiratory irritation.Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
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Suppliers and Manufacturers' Representative:
9910 Bent Oak Dr
Houston, TX 77040, USA
Call Toll Free: 1-855-55-AMMOL 1-855-552-6665
Email: info@ammol.org
20 August, 2026