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Thiamine Hydrochloride or Vitamin B1 Hydrochloride or Aneurine Hydrochloride
CAS Number: 67-03-8
Molecular Formula: C12H17N4OSCl-HCl
Molecular Weight: 337.27
Thiamine Hydrochloride or Vitamin B1 Hydrochloride or Aneurine Hydrochloride
Thiamine Hydrochloride USP Grade Specifications:
C12H17ClN4OS-HCl -- 337.27
Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride;
Thiamine monohydrochloride CAS 67-03-8
UNII: M572600E5P
UNII: X66NSO3N35
DEFINITION
Thiamine Hydrochloride contains NLT 98.0% and NMT 102.0% of thiamine hydrochloride (C12H17ClN4OS ·HCl), calculated on the anhydrous basis.
IDENTIFICATION
A. Infrared Absorption.
B. Identification Tests—General, Chloride: A 20-mg/mL solution meets the requirements.
Residue on Ignition: NMT 0.2%
Limit of Nitrate:
Sample solution: 20 mg/mL of Thiamine Hydrochloride
Analysis: To 2 mL of the Sample solution add 2 mL of sulfuric acid. Cool, and superimpose 2 mL of ferrous sulfate TS.
Acceptance criteria: No brown ring is produced at the junction of the two layers.
Related Compounds: To pass the chromatographic test.
pH: 2.7 to 3.4 in 10-mg/mL solution.
Water Determination: NMT 5.0%
Absorbance of Solution: To pass the test.
Thiamine Hydrochloride FCC Food Grade Specifications:
Aneurine Hydrochloride; Thiamine Chloride; Vitamin B1;
Vitamin B1 Hydrochloride
C12H17ClN4OS-HCl Formula weight 337.27
CAS 67-03-8
DESCRIPTION
Thiamine Hydrochloride occurs as small, white to yellow-white crystals or crystalline powder. When exposed to air, the anhydrous product rapidly absorbs about 4% of water. It melts at about 248C with some decomposition. One-gram dissolves in about 1 mL of water and in about 100 mL of alcohol. It is soluble in glycerin and is insoluble in ether.
Function: Nutrient.
Identification
A. The infrared absorption spectrum of a potassium bromide dispersion of the sample, previously dried at 105C for 2 h, exhibits relative maxima at the same wavelengths as those of a similar preparation of USP Thiamine Hydrochloride Reference Standard.
B. A 1:50 aqueous solution gives positive tests for Chloride,
Color of Solution: Passes test.
Lead: Not more than 2 mg/kg.
Nitrate: Passes test.
pH of a 1:100 Solution: Between 2.7 and 3.4.
Residue on Ignition: Not more than 0.2%.
Water: Not more than 5.0%.
We also supply Thiamine Hydrochloride BP Ph Eur Grade.
American Molecules, also known as ammol.org is a distributor, supplier and manufacturers' representative of all types of Pharmaceuticals, Functional Ingredients, Excipients and Specialty Chemicals in Texas USA. Our principals manufacture supply and export USP NF BP, Ph Eur, etc grades of chemicals pure and reagent grade, mineral fortifiers, FCC food grade. Tailor made particle size and customized specifications are offered. The principal's facility is having one or more of the certifications like FDA approval and GLP, cGMP, ISO9001, ISO14001, ISO/IEC 17025, ISO22000, FSSC 22000, ISO45001, FSSAI, Kosher, HALAL, COPP, WHO-GMP certified and Written Confirmation (WC) for export to Europe is available. The manufacturers suppliers and exporters observe WHO Good Manufacturing Practices and Good Laboratory Practices.
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